In addition to the functional IP cores, today?s SOC necessitates embedding a special family of IP blocks, called Infrastructure IP blocks. These are meant to ensure the manufacturability of the SOC and to achieve adequate levels of yield and reliability. The Infrastructure IP leverages the manufacturing knowledge and feeds back the information into the design phase. This keynote address analyzes the key trends and challenges resulting in manufacturing susceptibility and field reliability that necessitate the use of such Infrastructure IP. Then, it concentrates on certain examples of such embedded IPs for detection, analysis and correction.