We present a statistical method that can swiftly identify, from the literature, sets of genes known to be associated with given diseases. It offers a comprehensive way to treat alias symbols, a statistical method for computing the relevance of the gene to the query, and a novel way to disambiguate gene symbols from other abbreviations. The method is illustrated by finding genes related to breast cancer.
Citation:
Lada A. Adamic, Dennis Wilkinson, Bernardo A. Huberman, Eytan Adar, "A Literature Based Method for Identifying Gene-Disease Connections," csb, pp.109, IEEE Computer Society Bioinformatics Conference (CSB'02), 2002