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Protein Conformational Search Using Bees Algorithm
May 13-May 15
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/AMS.2008.652008 Second Asia International Confer ...
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Proteins perform many biological functions in the human body. The structure of the protein determines its function. In order to predict the protein structure computationally, protein must be represented in a proper representation. To this end, an energy function is used to calculate its energy and a conformational search algorithm is used to search the conformational search space to find the lowest free energy conformation. In this paper, the Bees Algorithm, i.e. a Swarm Intelligence based algorithm inspired by the foraging behaviour of honey bees colony, is adapted to search the protein conformational search space. The algorithm was able to find the lowest free energy conformation of Met enkephaline using ECEPP/2 force fields.
Index Terms:
Bees Algorithm, Protein Conformation, Swarm Intelligence
Citation:
Hesham Awadh Abdallah Bahamish, Rosni Abdullah, Rosalina Abdul Salam, "Protein Conformational Search Using Bees Algorithm," ams, pp.911-916, 2008 Second Asia International Conference on Modelling & Simulation, 2008
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