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Invited Talk: Steps Toward the Development of a Chronic Retinal Implant
Cambridge, Massachusetts, U.S.A April 03-April 05
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/BSN.2006.36International Workshop on Wearable an ...
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This talk describes the efforts at MIT and the Massachusetts Eye and Ear Infirmary over the past 15 years to develop a chronically implantable retinal prosthesis. The goal is to restore some useful level of vision to patients suffering from outer retinal diseases, primarily retinitis pigmentosa and macular degeneration. We initially planned to build an intraocular implant, wirelessly supplied with signal and power, to stimulate the surviving cells of the retina. In this design electrical stimulation is applied through an epiretinal microelectrode array attached to the inner (front) surface of the retina. We have carried out a series of six acute surgical trials on human volunteers (five of whom were blind with retinitis pigmentosa and one with normal vision and cancer of the orbit) to assess electrical thresholds and the perceptions resulting from epiretinal retinal stimulation. The reported perceptions often corresponded poorly to the spatial pattern of the stimulated electrodes. In particular, no patient correctly recognized a letter. We hope that chronically implanted patients will adapt over time to better interpret the abnormal stimuli supplied by such a prosthesis.
Citation:
John Wyatt, "Invited Talk: Steps Toward the Development of a Chronic Retinal Implant," bsn, pp.107, International Workshop on Wearable and Implantable Body Sensor Networks (BSN'06), 2006
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