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Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis
Amsterdam, Netherlands December 04-December 06
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/E-SCIENCE.2006.91Second IEEE International Conference ...
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Marcia A. Inda, Adam S.Z. Belloum, Marco Roos, Dmitry Vasunin, Cees de Laat, L.O. Hertzberger, Timo M. Breit, "Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis," e-Science and Grid Computing, International Conference on, pp. 19, Second IEEE International Conference on e-Science and Grid Computing (e-Science'06), 2006.
 
 
BibTex
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@article{ 10.1109/E-SCIENCE.2006.91,
author = {Marcia A. Inda and Adam S.Z. Belloum and Marco Roos and Dmitry Vasunin and Cees de Laat and L.O. Hertzberger and Timo M. Breit},
title = {Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis},
journal ={e-Science and Grid Computing, International Conference on},
volume = {0},
year = {2006},
isbn = {0-7695-2734-5},
pages = {19},
doi = {http://doi.ieeecomputersociety.org/10.1109/E-SCIENCE.2006.91},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
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TY - CONF
JO - e-Science and Grid Computing, International Conference on
TI - Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis
SN - 0-7695-2734-5
SP
EP
A1 - Marcia A. Inda,
A1 - Adam S.Z. Belloum,
A1 - Marco Roos,
A1 - Dmitry Vasunin,
A1 - Cees de Laat,
A1 - L.O. Hertzberger,
A1 - Timo M. Breit,
PY - 2006
KW - null
VL - 0
JA - e-Science and Grid Computing, International Conference on
ER -
 
Marcia A. Inda, University of Amsterdam, the Netherlands
Adam S.Z. Belloum, University of Amsterdam, the Netherlands
Marco Roos, University of Amsterdam, the Netherlands
Dmitry Vasunin, University of Amsterdam, the Netherlands
Cees de Laat, University of Amsterdam, the Netherlands
L.O. Hertzberger, University of Amsterdam, the Netherlands
Timo M. Breit, University of Amsterdam, the Netherlands
Explorative research is a vital part of biological sciences. Biologists frequently have to examine and compare multiple (large) sets of biological data in an interactive and explorative manner. Exploring alternative ways of examining the data and managing the necessary resources often require substantial (manual) effort and time.

In this paper, we present a concrete example of how VLAM, a grid-based workflow management system, can enhance experimentation. We discuss in detail the process of developing the SigWin-detector, an application in the domain of bioinformatics. We show that SigWin-detector can promptly identify regions of increased gene expression in transcriptome maps and periodicity in weather data. We also show that the workflow can be extended or partially modified. The individual modules can also be used to compose different experiments. SigWin-detector fulfills the requirements of interactive and explorative experimentation.

Citation:
Marcia A. Inda, Adam S.Z. Belloum, Marco Roos, Dmitry Vasunin, Cees de Laat, L.O. Hertzberger, Timo M. Breit, "Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis," e-science, pp.19, Second IEEE International Conference on e-Science and Grid Computing (e-Science'06), 2006
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