The Web Service Resource Framework (WS-RF) specifications originated from the Grid paradigm which has no widespread programming methodology and lacks established design models. The flexibility and richness of WS-RF specifications are ideal for the complex, unpredictable and inter-dependent components in an Enterprise Application. This paper presents a Model-Driven approach for WS-RF to meet the requirements of Enterprise Applications (EAs) spread across multiple domains and institutes. This Model-Driven approach addresses cross-platform interoperability, quality of service, design reuse, systematic development and compliance to user requirements at the design level.