Further progress of Biology and Medical Sciences requires successful integration with Computational and Information Sciences. The papers of this Mini-track provide a diverse spectrum of innovative ways of how such integration can be achieved. The focus of this mini-track is on the development and implementation of advanced data management tools in Biomedical Informatics. The first three papers in the mini-track focus on the development and implementation of computational and IT tools for Biomedical Informatics, while the forth paper presents advanced statistical methods for data analysis.