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Searching Similar Modules in Protein Interaction Netwo
Tokyo, Japan April 05-April 08
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/ICDE.2005.27921st International Conference on Data ...
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Hiroyuki Oka, Masanori Arita, "Searching Similar Modules in Protein Interaction Netwo," Data Engineering Workshops, 22nd International Conference on, pp. 1158, 21st International Conference on Data Engineering Workshops (ICDEW'05), 2005.
 
 
BibTex
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@article{ 10.1109/ICDE.2005.279,
author = {Hiroyuki Oka and Masanori Arita},
title = {Searching Similar Modules in Protein Interaction Netwo},
journal ={Data Engineering Workshops, 22nd International Conference on},
volume = {0},
year = {2005},
isbn = {0-7695-2657-8},
pages = {1158},
doi = {http://doi.ieeecomputersociety.org/10.1109/ICDE.2005.279},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
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TY - CONF
JO - Data Engineering Workshops, 22nd International Conference on
TI - Searching Similar Modules in Protein Interaction Netwo
SN - 0-7695-2657-8
SP
EP
A1 - Hiroyuki Oka,
A1 - Masanori Arita,
PY - 2005
KW - null
VL - 0
JA - Data Engineering Workshops, 22nd International Conference on
ER -
 
Hiroyuki Oka, Grad School of Frontier Sciences, Univ of Tokyo
Masanori Arita, Institute for Advanced Biosciences, Keio University, and PRESTO, JST
We developed a new method to search protein networks functionally similar to a given query signal transduction pathway within protein interaction networks. This method consists of two parts: 1) a backtracking search algorithm to find topologically identical subgraphs and 2) a measurement of similarity between proteins by using Gene Ontology [1]. For validation of our method, we implemented a software tool and compared its performance with that of PathBLAST [2] on the search of MAPK signal transduction cascades [3]. The result showed that our software tool has equal or better performance than that of PathBLAST.
Citation:
Hiroyuki Oka, Masanori Arita, "Searching Similar Modules in Protein Interaction Netwo," icdew, pp.1158, 21st International Conference on Data Engineering Workshops (ICDEW'05), 2005
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