Abstract: Computational biomechanics has been recognized as a powerful tool for cardiovascular research, vascular surgery planning and medical device design. An accurate and efficient construction of anatomic models is a critical element in the application of these computational methods. We developed an interactive modeling system. The novel features of this system were real time volume rendering and multi-resolution mesh editing. Using these capabilities, a medical expert became able to efficiently make accurate models using one's anatomical knowledge and heuristic ability, without requiring a background in intensive computation.