This paper describes a biologically-inspired architecture, called SymbioticSphere, which allows large-scale server farms to autonomously adapt to dynamic environmental changes and survive partial system failures. Symbiotic- Sphere follows biological principles such as decentralization, autonomy, natural selection, emergence and symbiosis to design server farms (application services and middleware platforms). Each application service and middleware platform is designed as a biological entity, analogous to an individual bee in a bee colony. Simulation results show that, like in biological systems, SymbioticSphere exhibits emergence of desirable system characteristics such as adaptability and survivability.